Symbol
Name
ID

Vegfa
vascular endothelial growth factor A
MGI:103178

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes

Increased circulating IgA level

Increased circulating IgG level

Decreased circulating antibody level

Paraproteinemia

Abnormality of blood and blood-forming tissues

Gastrointestinal hemorrhage

Retinal hemorrhage

Cerebral hemorrhage

Bruising susceptibility

Anemia

Leukocytosis

Abnormal granulocyte morphology

Abnormal basophil morphology

Ph-positive acute lymphoblastic leukemia

Acute myeloid leukemia

Chronic myelogenous leukemia

Myeloproliferative disorder

Abnormality of thrombocytes

Thrombocytopenia

Thrombocytosis

Multiple myeloma

Splenomegaly

Hepatosplenomegaly

Disease(s) Associated with VEGFA

acute myeloid leukemia

chronic myeloid leukemia

multiple myeloma

pre-eclampsia

pseudoxanthoma elasticum

Mouse Phenotypes

enhanced leukocyte tethering or rolling

abnormal leukocyte adhesion

abnormal thymus morphology

thymus hypoplasia

athymia

ectopic thymus

extramedullary hematopoiesis

anemia

increased mast cell number

decreased lymphocyte cell number

increased macrophage cell number

pancytopenia

Availability

Mouse Genotype

Vegfa^tm1Pec/Vegfa^tm1Pec

Vegfa^tm2.1Nagy/Vegfa^tm2.1Nagy

Tg(KRT14-Vegfa)3Dtm/0

Vegfa^tm2Gne/Vegfa^tm2Gne
Tg(Mx1-cre)1Cgn/0 (conditional)

Vegfa^tm2Gne/Vegfa⁺
Tg(Nphs1-cre)1Seq/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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